What is "pozanicline"

n. A drug with nootropic and neuroprotective effects.

Pozanicline (ABT-089) is a drug developed by Abbott, that has nootropic and neuroprotective effects. Animal studies suggested it useful for the treatment of ADHD and subsequent human trials have shown ABT-089 to be effective for this application. It binds with high affinity subtype-selective to the αβ nicotinic acetylcholine receptors and has partial agonism to the αβ subtype, but not the α and αβ subtypes familiar to nicotine. It has particularly low tendency to cause side effects compared to other drugs in the class -making it an exciting candidate for clinical development.