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POLI

DNA polymerase iota is an enzyme that in humans is encoded by the POLI gene. It is found in higher eukaryotes, and is believed to have arisen from a gene duplication from Pol η. Pol ι, is a Y family polymerase that is involved in translesion synthesis. It can bypass 6-4 pyrimidine adducts and abasic sites and has a high frequency of wrong base incorporation. Like many other Y family polymerases Pol ι, has low processivity, a large DNA binding pocket and doesn't undergo conformational changes when DNA binds. These attributes are what allow Pol ι to carry out its task as a translesion polymerase. Pol ι only uses Hoogsteen base pairing, during DNA synthesis, it will add adenine opposite to thymine in the syn conformation and can add both cytosine and thymine in the anti conformation across guanine, which it flips to the syn conformation.

Poli (surname)

Poli is a surname of Italian origin. The name refers to:

  • Afro Poli (1902–1988), Italian operatic baritone
  • Andrea Poli (b. 1989), Italian professional football player
  • Antonio De Poli (b. 1960), Italian politician; member of the European Parliament
  • Barbara Fusar-Poli (b. 1972), Italian ice dancer
  • Dante Poli (b. 1967), Argentine professional football player
  • Eros Poli (b. 1963), Italian professional road bicycle racer
  • Fausto Poli (1581–1653), Italian Roman Catholic archbishop; private secretary to Pope Urban VIII
  • Giuseppe Saverio Poli (1746–1825), Italian scientist
  • Jacopo Poli (contemporary), Italian manager of the Poli Distillerie grappa distillery
  • Ninsun Poli (contemporary), Assyrian singer and songwriter in Sweden
  • Piero Poli (b. 1960), Italian Olympic rower
  • Riccardo Poli (contemporary), Italian computer scientist and professor
Poli (Tanzanian ward)

Poli is an administrative ward in the Arumeru district of the Arusha Region of Tanzania. According to the 2002 census, the ward has a total population of 8,659.

Usage examples of "poli".

The pirate, politest of them all, was making a pretense of eating a lobster claw.

Hornblower put on his politest manner and took off his hat with his politest bow as he thanked them and escorted them to the side.