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Peirson may refer to:

  • Peirson Mitchell Hall (1894–1979), head of the U.S. Selective Service System for Los Angeles in 1941, federal District Court judge 1942–1979
  • Henry Peirson Harland (1876–1945), unionist politician in Northern Ireland
  • Francis Peirson (1757–1781), as a British Army officer who served during the American War of Independence
  • Johnny Peirson (born 1925), retired National Hockey League player