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n. An investigational anticancer drug.


Pegdinetanib ( USAN; planned trade name Angiocept) is an investigational anti-cancer drug that acts as a selective antagonist of vascular endothelial growth factor receptor 2 (VEGFR-2), hindering vascularization of tumors. It is a genetically engineered peptide derivative based on the monobody technology, and is being developed by Adnexus.

The drug has entered Phase II clinical trials investigating the treatment of glioblastoma in October 2007. , it is also in Phase II trials for the treatment of non-small cell lung cancer and colorectal cancer.