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Pcom or PCOM may refer to:

  • Pcom Network, an Internet Service Provider based in Tehran Province, Iran
  • P-Com, a defunct radio-networking manufacturer
  • Pacific College of Oriental Medicine
  • Philadelphia College of Osteopathic Medicine, in the United States
  • Posterior communicating artery, a blood vessel in the brain often referred to as the 'p-com'
  • Prison Commission (England and Wales)