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PCOA or PCoA may refer to:

  • Plasmid-encoded copper resistance determinant, an Escherichia coli operon responsible for copper homeostasis
  • Police Civilian Oversight Authority, a Jamaican body entitled to monitor the Police Forces
  • Posterior communicating artery, a pair of blood vessels in the circle of Willis
  • Principal coordinates analysis (or classical multidimensional scaling), a statistical method used to explore similarities in data set
    • Principal component analysis (abbreviated usually as PCA), a related mathematical procedure of data conversion into linearly uncorrelated variables
  • Proprietary Change of Address, a type of service offered by commercial providers that supplement National Change Of Address database