What is "pazinaclone"

n. A sedative and anxiolytic cyclopyrrolone drug.

Pazinaclone (DN-2327) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Some other cyclopyrrolone drugs include zopiclone and eszopiclone.

Pazinaclone has a very similar pharmacological profile to the benzodiazepines including sedative and anxiolytic properties, but with less amnestic effects, and at low doses it is a relatively selective anxiolytic, with sedative effects only appearing at higher doses.

Pazinaclone produces its sedative and anxiolytic effects by acting as a partial agonist at GABA benzodiazepine receptors, although pazinaclone is more subtype-selective than most benzodiazepines.