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PatternHunter

PatternHunter is a commercially available homology search instrument software that uses sequence alignment techniques. It was initially developed in the year 2002 by three scientists: Bin Ma, John Tramp and Ming Li. These scientists were driven by the desire to solve the problem that many investigators face during studies that involve genomics and proteomics. These scientists realized that such studies greatly relied on homology studies that established short seed matches that were subsequently lengthened. Describing homologous genes was an essential part of most evolutionary studies and was crucial to the understanding of the evolution of gene families, the relationship between domains and families. Homologous genes could only be studied effectively using search tools that established like portions or local placement between two proteins or nucleic acid sequences. Homology was quantified by scores obtained from matching sequences, “mismatch and gap scores”.