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Douglas Harper's Etymology Dictionary
patootie

"sweetheart, pretty girl," colloquial American English, 1921, perhaps a corruption of potato (c.f. sweet potato). Sweet patootie is recorded from 1919 as a generic exclamation.

Wiktionary
patootie

n. 1 (context chiefly US slang English) The buttocks. 2 (context chiefly US slang English) An attractive girl; a girlfriend.

Usage examples of "patootie".

Kerr and Burt Lancaster must have frozen their patooties off making that scene.

He was just there, for once not scampering after his deceased Persian patootie, but stalking along at my heel, all dignity now, sort of convoying me like a tugboat, escorting me—where?

I wore a lot of sweaters in the winter, but tonight I'd wanted something dressier, and I was freezing my patooties off, but I was hoping that Richard would like the red blouse.

The big beefy dykes took as long as they liked and if you had objections, tough patooties to you.