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pachygyria

n. congenital malformation of the cerebral hemisphere, resulting in unusually thick convolutions of the cerebral cortex and typically causing developmental delay and seizures

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Pachygyria

Pachygyria (from the Greek "pachy" meaning "thick" or "fat" gyri) is a congenital malformation of the cerebral hemisphere. It results in unusually thick convolutions of the cerebral cortex. Typically, children have developmental delay and seizures, the onset and severity depending on the severity of the cortical malformation. Infantile spasms are common in affected children, as is intractable epilepsy.