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PABPI, from its complete name polyadenylate binding protein I, is localized in the cell cytoplasm. As the name implies, its main function is to bind to the poly(A) tail of mature messenger RNAs (mRNAs). During protein synthesis, a stage known as translation, PABPI interacts with both the mRNA's poly(A) tail and eukaryotic initiation factor 4G (eIF4G), forming a round structure, which is thought to increase stability.