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OTK may refer to:

  • Accident Investigation Board of Finland (Onnettomuustutkintakeskus)
  • One Time Key, a method related to encryption
  • One Turn Kill
  • Open Tool Kit, a graphical user interface library
  • Otakuthon, Montreal's anime convention (OTK is pronounced as "O-tak")
  • Language code for Old Turkish
  • Over The Knee
  • Over-the-knee boots ("OTK boots")
  • Ottakring, the 16th municipal district of Vienna