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The Collaborative International Dictionary
osteoclast

osteoclast \os"te*o*clast\, n. [Osteo- + Gr. kla^n to break.]

  1. (Physiol.) Same as myeloplax, a large multinucleate cell within the bone, which functions in the absroption and removal of bone tissue.

    Note: The osteoclasts occur usually in pits or cavities which they appear to have excavated, and are supposed to be concerned in the absorption of the bone matrix.

  2. An instrument for performing osteoclasis.

Wiktionary
osteoclast

n. 1 (context physiology cytology English) A large multinuclear cell associated with the resorption of bone 2 (cx surgery English) An instrument for performing osteoclasis.

WordNet
osteoclast

n. cell that functions in the breakdown and resorption of bone tissue

Wikipedia
Osteoclast

An osteoclast (from the Greek words for "bone" (ὀστέον), and "broken" (κλαστός)) is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodelling of bones of the vertebral skeleton. The osteoclast disassembles and digests the composite of hydrated protein and mineral at a molecular level by secreting acid and a collagenase, a process known as bone resorption. This process also helps regulate the level of blood calcium.

An odontoclast (/odon·to·clast/; o-don´to-klast) is an osteoclast associated with absorption of the roots of deciduous teeth.

Usage examples of "osteoclast".

We confirmed that the osteoclast gene was responsible for the degradative enzyme and also showed that it is not expressed in other tissues.

Human Genome Sciences to help them analyze some genetic material they had isolated from the osteoclast cells of people with bone tumors.

Once they found near-matches for the sequences, they carried out further analyses and discovered that one sequence in particular was overexpressed by the osteoclast cells and that it matched those of a previously identified class of molecules: cathepsins.

I took them up, one by one, the hook, the probe, the cannula, the perforator, the hammer, the osteoclast, the dipyrene, the spathomele and, last of all, the scalpel.

Following in the wake of the osteoclasts are cells calledosteoblasts, which enter these pores and begin construction of new bone tissue.

Osteoporosis means basically that the osteoclasts are outrunning the osteoblasts, resulting in a relative loss of bone tissue.

First, City carves out skeletons for them (politely ignoring a crudely phrased request to cease and desist from Pamela, on the grounds that she has no power of attorney), then squirts osteoclasts into the spongy ersatz bone.