Osirus may refer to:
- Osirus (album) (2005), final album from Ol' Dirty Bastard before his death in 2004
- Ol' Dirty Bastard, as a nickname for the American rapper
- Pottery "Osirus ", former pottery from Gouda, the Netherlands. Founded in 1930 by W. van der Kroef, producer of Delft Pottery, Experimental Art Pottery and Contemporary Pottery
Osirus is a posthumous mixtape album by Ol' Dirty Bastard released on January 4, 2005.