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The Collaborative International Dictionary
Orthopny

Orthopnoea \Or`thop*n[oe]"a\, Orthopny \Or*thop"ny\, n. [L. orthopnoea, Gr. ?; 'orqo`sstraight, right + pnei^n to breathe: cf. F. orthopn['e]e.] (Med.) Specifically, a morbid condition in which respiration can be performed only in an erect posture; by extension, any difficulty of breathing.

Wiktionary
orthopny

n. (context medicine dated English) orthopnoea