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Oncophage

Oncophage is a personalized cancer vaccine by the American company Antigenics Inc. that is evaluated in multiple clinical trials. It has been granted fast track and orphan drug designations from the US Food and Drug Administration for kidney cancer, metastatic melanoma, and glioma.

Oncophage is not yet approved in the USA but was approved in Russia in April 2008 for patients who have earlier-stage kidney cancer. The European Medicines Agency is evaluating conditional approval for Oncophage.

Oncophage is one of a group of new drugs called cancer vaccines that intend to train the body's immune system to fight the cancer. While chemotherapy is often accompanied by severe side effects, cancer vaccines tend to have only minimal ones (often only inflammations of the injection site).

In April 2009, the World Vaccine Congress named Oncophage as the best therapeutic vaccine.