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Douglas Harper's Etymology Dictionary
O.D.

abbreviation of overdose, attested from 1960.

WordNet
o.d.

v. dose too heavily; "The rock star overdosed and was found dead in his hotel room" [syn: overdose]

Wikipedia
O.D. (musician)

O.D. is one of the founders of the industrial/ metal/ electronic band Velcra. He has worked on samples/programming and guitars on the band's first two albums and is the main producer on their third album.