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NRB is an acronym, abbreviation, or initialism that may refer to:

  • National Reconstruction Bureau, Defunct Pakistani government institution for economic recovery and prosperity
  • National Religious Broadcasters, international association of Christian communicators
  • Nederlandse Rugby Bond, Dutch rugby union governing body
  • Nepal Rastra Bank, central bank of Nepal
  • New Research Building, Harvard University biomedical research facility
  • Non-rebreather mask, device used for emergency oxygen therapy
  • Norbury railway station, England (station code NRB)
  • People's Republic of Bulgaria (, Narodna republika Bulgaria)
  • Navigating Rensselaer and Beyond, Rensselaer Polytechnic Institute freshman orientation week.