Wikipedia
In biochemistry, the native state of a protein or nucleic acid is its properly folded and/or assembled form, which is operative and functional. The native state of a biomolecule may possess all four levels of biomolecular structure, with the secondary through quaternary structure being formed from weak interactions along the covalently-bonded backbone. This is in contrast to the denatured state, in which these weak interactions are disrupted, leading to the loss of these forms of structure and retaining only the biomolecule's primary structure.
An alternate usage in metallurgy refers to metals which are found chemically uncombined in nature.
Usage examples of "native state".
In its native state the Auricula is said to be either yellow or white.
So I learned then, once for all, that gold in its native state is but dull, unornamental stuff, and that only low-born metals excite the admiration of the ignorant with an ostentatious glitter.
A peaceful native state, ruled by a charming young woman whose grievances were petty enough, and who gave most of her time to seducing the affections of a dashing British colonel.
To distinguish it from the other Sweet Clovers, it is called Hubam, after Professor Hughes, its discoverer, and Alabama, its native state.
Because, by that time our University will be compleate and in full action: and you would recieve the satisfaction, in the final adieu to your native state, of seeing that she would retain her equal standing in the sisterhood of our republics.
With the money he went back to his native state, Kansas, where he bought a farm and led an easy life.
He never returned to his native state of Georgia because he thought he would be hung for what the Texas did.