Wikipedia
Myospherulosis
Myospherulosis, also known as spherulocytosis, is a foreign body-type granulomatous reaction to lipid-containing material and blood.
It may be seen in various settings including:
- Fat necrosis.
- Malignancy, e.g. renal cell carcinoma.
- Placement of topical tetracycline in a petrolatum base into a surgical site.
The resultant histopathologic pattern is most unusual and initially was mistakenly thought to represent a previously undescribed endosporulating fungus.