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Myeloblastin

Myeloblastin (, leukocyte proteinase 3, leukocyte proteinase 4, Wegener's granulomatosis autoantigen, proteinase PR-3, proteinase-3, PMNL proteinase) is an enzyme. This enzyme catalyses the following chemical reaction

Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala- > -Val-

This enzyme is present in polymorphonuclear leukocyte granules.