MVF can refer to:
- Man v. Food, a TV series
- Main Variable Figure, a type of fictional mobile suit (see List of Mobile Suit Gundam SEED mobile weapons)
- mvf, the ISO 639-3 code for the Peripheral Mongolian language
- Mouse virulence factor (MVF) family of transport proteins belonging to the MOP flippase superfamily.
- Mamidipudi Venkatarangaiya Foundation