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muscarine

n. (context biochemistry English) An extremely poisonous alkaloid, obtained from fly agaric, that disrupts the action of acetylcholine neurotransmitter.

Wikipedia
Muscarine

Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species, such as the deadly C. dealbata. Mushrooms in the genera Entoloma and Mycena have also been found to contain levels of muscarine which can be dangerous if ingested. Muscarine has been found in harmless trace amounts in Boletus, Hygrocybe, Lactarius and Russula. Muscarine is only a trace compound in the fly agaric Amanita muscaria; the pharmacologically more relevant compound from this mushroom is muscimol. A. muscaria fruitbodies contain a variable dose of muscarine, usually around 0.0003% fresh weight. This is very low and toxicity symptoms occur very rarely. Inocybe and Clitocybe contain muscarine concentrations up to 1.6%.

Muscarine is a nonselective agonist of the muscarinic acetylcholine receptor.

Usage examples of "muscarine".

They were called muscarinic because they mirrored- the effect of a drug called muscarine, which came from a type of mushroom.

Mescaline, harmaline, LSD6, bufotenine, muscarine successful in many cases.

Some of them are analogous in action to muscarine, the active principle of the fly fungus.

Many of the symptoms associated with nicotine were the same as those caused by muscarine: salivation, sweating, abdominal pain, and lacrimation-the very same symptoms that had appeared in Patty Owen and Henry Noble.

They were called muscarinic because they mirrored- the effect of a drug called muscarine, which came from a type of mushroom.