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MPAC or Mpac may refer to:

  • The Malaria Policy Advisory Committee
  • The Municipal Property Assessment Corporation, headquartered in Pickering, Ontario, Canada
  • The Muslim Public Affairs Council, headquartered in Los Angeles, California, United States
  • The Muslim Public Affairs Committee UK, headquartered in the United Kingdom
  • The Malawi Public Affairs Committee, a Muslim religious body in Malawi
  • The Metropolitan Performing Arts Center in Spokane, Washington, United States
  • The Manufacturers' Political Action Committee of the Illinois Manufacturers' Association
  • The Multi-purpose Attack Craft, a class of fast military assault boat by the Philippine Navy