What is "methylergometrine"

n. (context chemistry English) A synthetic analogue of ergonovine with oxytocic properties.

Methylergometrine (other names include methylergonovine, methylergobasin, methergine, and D- lysergic acid 1- butanol amide) is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergometrine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams, due to its agonistic action at the 5HT- mGlu2 receptor protomers. Clinical efficacy occurs around 200 µg, ten times lower than the hallucinogenic threshold.

Methylergometrine maleate is marketed under the trade name Methergine.