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Meiomitosis

During normal mitosis, sister chromatids separate into two identical daughter cells. In meiosis is a diploid cell (2N) duplicates its DNA once and undergoes two rounds of cell division to produce four haploid (1N), germ cells that promotes the recombination of large expanses of chromosomal DNA, potentially similar in size to those lost or gained in cancer In meiotic division, homologous chromosomes are held together by cohesions, and after resolution of chiasma (the recombination crossover points with the other chromosome pair), the homologous chromosomes are segregated together.Meiomitosis is an aberrant cellular division pathway through which daughter cells following mitosis inherit partially expressed meiotic machinery. In these cells chiasma occurs and sister chromatids are partly held together by cohesions; when cell division occurs, the sister chromatids are sheared and mis-segregated which results in an aneuploid state.