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Longman Dictionary of Contemporary English
mediator
noun
COLLOCATIONS FROM CORPUS
■ ADJECTIVE
inflammatory
▪ Other differences have been previously described with respect to the generation of other inflammatory mediators.
▪ This is not surprising considering that most inflammatory mediators have been shown to be able to stimulate enteric nerves.
▪ The rise in eicosanoid inflammatory mediators may have an important role in the pathophysiology of the early radiation bowel reaction.
▪ The superoxide generated may have a direct cytotoxic effect or it may interact with inflammatory mediators to modify the inflammatory process.
▪ Ketotifen may prevent the release of the inflammatory mediators from mast cells as well as from other inflammatory cells.
■ VERB
act
▪ If two adults are playing roles they can adopt quite a confrontational stance, challenging the children to act as mediators.
▪ She had created the situation in which the pupils had learned, had acted as mediator and had controlled their learning process.
▪ Conflict manager: resolving disputes, acting as a mediator. 7.
▪ They are subject to regulation by many neural, hormonal, and paracrine factors, acting via intracellular mediators.
EXAMPLES FROM CORPUS
▪ I see no basis for meaningful comparison between solicitors and mediators.
▪ There is also an independent service with trained mediators, most of them solicitors.
▪ There were no official mediators, licensed by an ecclesiastical hierarchy or set apart by apostolic ordination.
The Collaborative International Dictionary
Mediator

Mediator \Me"di*a`tor\, n. [L. mediator: cf. E. m['e]diateur.] One who mediates; especially, one who interposes between parties at variance for the purpose of reconciling them; hence, an intercessor.

For there is one God, and one mediator between God and men, the man Christ Jesus.
--1 Tim. ii. 5.

Douglas Harper's Etymology Dictionary
mediator

mid-14c., from Late Latin mediatorem (nominative mediator) "one who mediates," agent noun from past participle stem of mediari "to intervene, mediate," also "to be or divide in the middle," from Latin medius "in the middle" (see medial (adj.)). Originally applied to Christ, who in Christian theology "mediates" between God and man. Meaning "one who intervenes between two disputing parties" is first attested late 14c. Feminine form mediatrix (originally of the Virgin Mary) from c.1400. Related: Mediatorial; mediatory.

Wiktionary
mediator

n. 1 One who negotiates between parties seeking mutual agreement 2 A chemical substance transmitting information to a targeted cell.

WordNet
mediator

n. a negotiator who acts as a link between parties [syn: go-between, intermediator, intermediary, intercessor]

Wikipedia
Mediator

Mediator may refer to:

  • A person who engages in mediation
  • Business mediator, a mediator in business
  • Vanishing mediator, a philosophical concept
  • Mediator variable, in statistics
Mediator (coactivator)

Mediator is a multiprotein complex that functions as a transcriptional coactivator in all eukaryotes. It was discovered by Roger D. Kornberg, winner of the 2006 Nobel Prize in Chemistry. It is also referred to in scientific literature as the vitamin D receptor interacting protein (DRIP) coactivator complex and the thyroid hormone receptor-associated proteins (TRAP).

The mediator complex is required for the successful transcription of nearly all class II gene promoters in yeast. It works in the same manner in mammals. The human Mediator complex has 31+ subunits and is 1.2 MDa in size. Its large surface area provides great potential for protein–protein interaction, even though its sequences do not contain many predicted functional domains. Mediator has been shown to associate with general transcription factors, as well as RNA polymerase II, and is essential for activator-dependent transcription. It has also been demonstrated that the Mediator complex is involved in activator-independent transcription, implying that it may provide a fundamental control of the formation of the initiation complex. Mediator functions as a coactivator and binds to the C-terminal domain of RNA polymerase II holoenzyme, acting as a bridge between this enzyme and transcription factors.

Mediator (software)

Mediator is a multimedia authoring tool for Windows, developed and distributed by MatchWare, first released in 1993.

Mediator has been registered and approved to be purchased by Electronic Learning Credits (eLCs) in the United Kingdom, as part of the Curriculum Online program It is also part of a DiDA software suite, along with MatchWare's other programs, OpenMind and ScreenCorder.

Usage examples of "mediator".

The Jewish speculations about Angels and Mediators, which at the time of Christ grew very luxuriantly among the Scribes and Apocalyptists, and endangered the purity and vitality of the Old Testament idea of God, were also very important for the development of Christian dogmatics.

Of course, the other side will have to agree to this plan, the mediator will have to be willing to arbitrate, and the proper agreements and disclosures will have to be signed by the parties.

In the second Degree, the Initiate was taught the Unity of the Godhead, the happiness of the patriarchs, the destruction by the Deluge, the depravity of the heart, and the necessity of a mediator, the instability of life, the final destruction of all created things, and the restoration of the world in a more perfect form.

Barbaro as a mediator between herself and her father, assuring me that she would rather die than become the wife of the monster who had dishonoured her.

Lafayette and for the Ideologues created the context in which Lafayette began to establish his new role as an intellectual mediator.

Tracy and the Ideologues thus gave him more than the chance to regain his status as an international mediator.

Mediator listened to the recording Victoria had made, the notice in trade Koine that the ship was salvage but that Medina Alliance would pay well for Jennifer and Terry.

The Mediator listened to the recording Victoria had made, the notice in trade Koine that the ship was salvage but that Medina Alliance would pay well for Jennifer and Terry.

Moses exceedingly trembled, but ye are come to Mount Zion, to the heavenly Jerusalem, and to an innumerable company of angels, and to God, and to the spirits of the perfected just, and to Jesus, the mediator of the new covenant, and to the lustral blood which speaks better things than that of Abel.

Although your estate be very weak, God is able to raise you, and make you reign, maugre the opposition of all your enemies: and howsoever it shall please the Lord to dispose, you shall have peace toward God, through Christ the Mediator.

If you are mediating in a court-sponsored program and the mediator has power to make a recommendation regarding child custody and visitation, this becomes all the more important.

Or, if you are a homeowner mediating against a contractor, a contractor mediator may be suspect in your eyes.

Tchicaya could see no other Yielders, but he resisted the urge to ask his Mediator to hunt for friendly signatures.

It was like that every morning: Brine arrived in the middle of a discussion and was immediately elected to the role of expert and mediator.

A sacrificial Mediator with Jehovah, that expiatory intercessor born from the chosen house of the chosen people, yet blending in his inexplicable nature the divine essence with the human elements, appointed before all time, and purifying, by his atoning blood, the myriads that preceded and the myriads that will follow us, without distinction of creed or clime, this is what you believe.