What is "meclofenamic acid"

n. A drug that inhibits the synthesis of prostaglandins, used to treat joint and muscle pain.

Meclofenamic acid (meclofenamate sodium, brand Meclomen) is a drug used for joint, muscular pain, arthritis and dysmenorrhea. It is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs and was approved by the FDA in 1980. Like other members of the class, it is a COX inhibitor and prevents formation of prostaglandins.

Scientists led by Claude Winder from Parke-Davis invented meclofenamate sodium in 1964, along with fellow members of the class, mefenamic acid in 1961 and flufenamic acid in 1963.

Patents on the drug expired in 1985 and several generics were introduced in the US, but as of July 2015 only Mylan still sold it.

It is not widely used in humans as it has a high rate (30-60%) rate of gastrointestinal side effects. As of 2015 the cost for a typical course of medication in the United States is 50 to 100 USD.