What is "malakoplakia"

n. A rare inflammatory condition, usually presenting a papule or ulceration affecting the genitourinary tract, and thought to result from the insufficient killing of bacteria by macrophages.

Malakoplakia or malacoplakia (from Latin Malako "soft" + Plako "plaque") is a rare inflammatory condition which makes its presence known as a papule, plaque or ulceration that usually affects the genitourinary tract. However, it may also be associated with other bodily organs. It was initially described in the early 20th century as soft yellowish plaques found on the mucosa of the urinary bladder. Microscopically it is characterized by the presence of foamy histiocytes with basophilic inclusions called Michaelis–Gutmann bodies.

It usually involves gram negative bacteria.