vb. (context idiomatic English) To attempt to escape; to flee; to run away.
Usage examples of "make a break for it".
It was so tempting, with the door open and the passageway out to the sun clear, to forget Gomm and the others and make a break for it.
He should wring her pretty little neck, grab the controller, and make a break for it.
They had talked it over and agreed that Doc would try to make a break for it.
Or one or the other will have to make a break for it to keep from being killed.