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Magnotech

Magnotech is a type of biosensor using magnetic nanoparticles to measure target molecules in blood and saliva in a matter of minutes. The technology is based on magnetic nanoparticles that are actuated by magnetic fields [1]. The aim is to expand the rapid diagnosis sector of the in vitro diagnostics market.

A cartridge is inserted into a hand-held analyzer. The cartridge is constructed entirely from plastic components, has no moving parts or embedded electronics, and is disposable. It automatically fills itself from a single drop of blood or saliva. Once filled, no other fluid movement is required. The entire assay process within the cartridge is executed by controlled movement of the magnetic nanoparticles, using magnetic fields generated by the hand-held analyzer. The analyzer unit contains the electromagnets, an optical detection system, control electronics, software and the read-out display. Tests have shown that the cardiac marker Troponin I can be measured in blood plasma in around five minutes.

The technology behind Magnotech was initiated by Philips Research Fellow, Menno Prins. In 2014 he became fulltime professor at Eindhoven University of Technology.

Magnotech is used in the Minicare system of Philips Handheld Diagnostics.

[1] Bruls et al, "Rapid integrated biosensor for multiplexed immunoassays based on actuated magnetic nanoparticles", Lab on a Chip, 2009,9, 3504-3510, DOI: 10.1039/B913960E

Category:Biotechnology