The Collaborative International Dictionary
Lupus \Lu"pus\, n. [L., a wolf. See Wolf.]
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(Med.) originally, a cutaneous disease with the appearance of the skin having been gnawed, and occurring under two distinct forms. Now used as a generic term for over ten distinguishable diseases having visible cutaneous symptoms.
Note: Lupus erythematosus is characterized by an eruption of red patches, which become incrusted, leaving superficial scars. Lupus vulgaris is marked by the development of nodules which often ulcerate deeply and produce great deformity. Prior to 1900 the latter was often confounded with cancer, and some varieties of cancer were included under Lupus. Systemic lupus erythematosus is an inflammatory connective tissue disease occurring mostly in women, characterized by skin rash, fever, and arthritic symptoms, and often accompanied by hemolytic anemia, inflammation of the pericardium, glomerular lesions, and hyperglobulinemia; the condition shows positive in the LE cell test.
--[Stedman]br/ [1913 Webster +PJC] (Astron.) The Wolf, a constellation situated south of Scorpio.
WordNet
n. tuberculosis of the skin; appears first on the face and heals slowly leaving deep scars
Wikipedia
Lupus vulgaris (also known as Tuberculosis luposa) are painful cutaneous tuberculosis skin lesions with nodular appearance, most often on the face around the nose, eyelids, lips, cheeks, ears and neck. It is the most common M. tuberculosis skin infection. The lesions may ultimately develop into disfiguring skin ulcers if left untreated.