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Wiktionary
lock and load

interj. 1 (context US slang English) (non-gloss definition: A command to prepare a weapon for battle.) 2 (context US slang English) prepare for an imminent event.

Wikipedia
Lock and Load

Lock and Load or Lock 'N Load may refer to:

In television:

  • Lock N' Load with R. Lee Ermey, a show about the history of military weaponry
  • Lock 'N Load (reality show), a reality show about the gun enthusiast lifestyle
  • "Lock & Load", a 2006 episode of The Colbert Report

In music:

  • Lock 'n Load (album), a comedy album by Denis Leary
  • T.O.S: Terminate on Sight or Lock and Load, an album by G-Unit
  • Lock & Load, an album by Leslie Fish
  • "Lock and Load", a song by Bob Seger from It's a Mystery
  • "Lock and Load", a song by Lil Wayne from Tha Carter II
  • "Lock and Load", a song by The Mess Hall from Feeling Sideways
  • "Lock and Load", a song by Snapper from A.D.M.
  • "Lock & Load", a song by Bone Crusher from AttenCHUN!
  • "Lock & Load", a song by D.S.G.B. from The Last Supper
  • "Lock-n-Load", a song by Layzie Bone from Thug by Nature
  • "Lock and Load" a song on the Devil May Cry Original Soundtrack
  • Lock 'n' Load (bluegrass band), fronted by Lionel (radio personality)

In games:

  • Lock 'N Load, a series of wargames by Mark H. Walker
  • Lock & Load: Character Primer, a source book for Iron Kingdoms

Usage examples of "lock and load".

Go ahead and pick up the magazine and seat it, then lock and load.

If you came near the barracks, a guy would scream, 'Lock and load!