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lipstatin

n. A potent, irreversible inhibitor of pancreatic lipase, first isolated from the actinobacterium ''Streptomyces toxytricini''.

Wikipedia
Lipstatin

Lipstatin is a potent, irreversible inhibitor of pancreatic lipase. It is a natural product that was first isolated from the Actinobacterium Streptomyces toxytricini.

The popular antiobesity drug orlistat (trade names Xenical and alli) is a saturated derivative of lipstatin.