The Collaborative International Dictionary
lipophobic
lipophobic \lipophobic\ adj. (Chem.) Not soluble in lipids, or in non-polar solvents; -- of chemical substances or parts of molecules; as, the lipophobic end of a detergent is solvated in water. Contrasted to lipophilic or nonpolar.
Wiktionary
lipophobic
a. (context chemistry English) Having no affinity for fats or organic solvents