What is "lesopitron"

n. A selective full agonist of the 5-HT1A receptor, structurally related to the azapirones, used as an anxiolytic.

Lesopitron (E-4424) is a selective full agonist of the 5-HT receptor which is structurally related to the azapirones. In 2001 it was under development by Esteve as an anxiolytic for the treatment of generalized anxiety disorder (GAD). It made it to phase II clinical trials but was apparently discontinued as no new information on lesopitron has surfaced since.