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Lasco or LASCO may refer to:

  • Lasco, California, United States
  • Lasco Jamaica, a food, financial, household and personal care and pharmaceutical company based in Kingston, Jamaica
  • Laboratory for the Analysis of Organisational Communication Systems, in Louvain-la-Neuve in Belgium
  • Large Angle and Spectrometric Coronagraph, an instrument on the Solar and Heliospheric Observatory satellite (SOHO)
  • Larkin Aircraft Supply Company, an Australian aircraft manufacturer
  • John a Lasco (1499–1560), Polish Protestant evangelical reformer