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lamellipodium

n. (context biology English) A cytoskeletal actin projection on the mobile edge of the cell.

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Lamellipodium

The lamellipodium (plural lamellipodia) (from Latin , "thin sheet"; pod, "foot") is a cytoskeletal protein actin projection on the leading edge of the cell. It contains a quasi-two-dimensional actin mesh; the whole structure propels the cell across a substrate. Within the lamellipodia are ribs of actin called microspikes, which, when they spread beyond the lamellipodium frontier, are called filopodia. The lamellipodium is born of actin nucleation in the plasma membrane of the cell and is the primary area of actin incorporation or microfilament formation of the cell.