Wiktionary
(context idiomatic slang English) pregnant, typically outside of marriage. v
(en-pastknock up)
Wikipedia
Knocked Up is a 2007 American romantic comedy film co-produced, written and directed by Judd Apatow. The films stars Seth Rogen, Katherine Heigl, Paul Rudd, Ken Jeong, Harold Ramis, and Leslie Mann. It follows the repercussions of a drunken one-night stand between a slacker and a just-promoted media personality that results in an unintended pregnancy. The film was released on June 1, 2007 and a spin-off sequel, This Is 40, was released in 2012.
Usage examples of "knocked up".
Crawford and the beauty of the weather, would soon have been knocked up now.
Of course they thought Matzerath had knocked up Maria and that's why he's marrying her though she's only seventeen and he's going on forty-five.
But I knew that he knew that I had no intention of staying there with those crazy people who knocked up their cousins and stayed about as ignorant as I ever saw.
He was hit and killed by a runaway donkey cart and knocked up on the curbing with his, how was it put in the book.