KCOT may refer to:
- KCOT (FM), a radio station (96.3 FM) licensed to serve Cotulla, Texas, United States
- Cotulla-La Salle County Airport (ICAO code KCOT)
- Keratocystic odontogenic tumour
KCOT is a radio station on 96.3 FM in Cotulla, Texas. It is owned by José Antonio Aguilar and carries the La Mejor Regional Mexican format from MVS Radio.