JMB may refer to:
- JMB, JeceMusicBand, Music Band
- John Moses Browning, Mormon small arms architect
- José Manuel Barroso, a European politician
- Jorge Mario Bergoglio, an Argentine Roman Catholic cardinal also known as Pope Francis
- JMB Communications, a Massachusetts communication company
- JMB Records, a record company
- JMB Realty, a Chicago real estate company
- Jamaat-ul-Mujahideen Bangladesh, an Islamic organization in Bangladesh
- the Joint Matriculation Board (earlier known as the Northern Universities Joint Matriculation Board), a body in the United Kingdom which awarded O levels and A levels.
- The JAL Mileage Bank, the frequent flyer program of Japan Airlines
- Johnson Matthey Bankers, the core of a 1984 banking crisis
- JMicron, a technology company. Linux reports their devices as JMB363 or similar.
- James M. Bennett High School, in Salisbury, Maryland
- Journal of Molecular Biology, a weekly scientific journal.