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JHC may refer to:

  • JHC , a Christogram
  • Jaffna Hindu College, a boys' public national school in Jaffna, Sri Lanka
  • Jesus H. Christ, an example of slang serving as a profanity
  • Jesus Henry Christ, a comedy based on Dennis Lee's Student Academy Award-winning short film of the same name
  • John Hancock Center, a 100-story, 1,127-foot tall skyscraper in Chicago, Illinois
  • Joint Helicopter Command, a tri-service organisation uniting military helicopters of the British Armed Forces
  • Journal of Higher Criticism, an academic journal
  • Journal of Histochemistry and Cytochemistry, a peer-reviewed scientific journal of cell biology
  • Jurong Health Connect, a community health project started in Jurong
  • JuraHealth Congress, an annual conference in Germany about health care legislation