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ISSOW stands for Integrated Safe System of Work. An Integrated Safe System of Work is used in hazardous industry to request, review, approve and document tasks to be carried out by frontline workers. It integrates Permit-To-Work, Risk Assessment and Isolation Management under a single electronic system, providing safety improvements to the user.

Thought to have originated in the North Sea upstream oil industry it was actually used several years before within the Power Industry, ISSoW software now forms a significant segment of the Enterprise Software market.