What is "isofuran"

n. (context biochemistry English) Any of various nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid, similar to the isoprostanes but with a substituted tetrahydrofuran ring.

Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.