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ISOC is an abbreviation which may refer to:

  • Information Security Operations Center, is a location where enterprise information systems are monitored, assessed, and defended.
  • Internet Society, ISoc, an international organization that promotes Internet use and access
  • Internal Security Operations Command, a unit of the Thai military devoted to national security issues
  • In Service Open Challenge, a Walt Disney World lifeguarding competition
  • Islamic Society, various Islamic-based groups