What is "ipledge"

The iPLEDGE program is a mandatory distribution program in the United States for isotretinoin (commonly sold under the trade names Roaccutane, Claravis, Absorica, Amnesteem, Myorisan, Sotret, or Zenatane), intended to prevent the use of the drug during pregnancy due to the high risk of birth defects (see Teratogenicity of isoretinoin). As of March 1, 2006, patients and their doctors and pharmacists are required by the U.S. Food and Drug Administration (FDA) to register and use a web site in order to receive this medication.