What is "imidazolonepropionase"

n. (context enzyme English) A hydrolase enzyme that catalyzes the chemical reaction ''(S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H₂O $rightleftharpoons$ N-formimidoyl-L-glutamate + H⁺''.

In enzymology, an imidazolonepropionase is an enzyme that catalyzes the chemical reaction

(S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + HO $\rightleftharpoons$ N-formimidoyl-L-glutamate + H

Thus, the two substrates of this enzyme are (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate and HO, whereas its two products are N-formimidoyl-L-glutamate and H.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase. Other names in common use include 4(5)-imidazolone-5(4)-propionic acid hydrolase, and imidazolone propionic acid hydrolase. This enzyme participates in histidine metabolism.