What is "igmesine"

n. A sigma receptor agonist with neuroprotective, antidepressant, and nootropic effects.

Igmesine (JO-1,784) is a sigma receptor agonist. It has neuroprotective and antidepressant effects in animal studies, as well as nootropic effects in models of age-related cognitive decline. It showed good results in phase I human clinical trials but has not been continued further.