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hydroxymethylbilane

n. (context biochemistry English) A molecule involved in the metabolism of porphyrin. It is generated by the enzyme porphobilinogen deaminase and then converted into uroporphyrinogen III.

Wikipedia
Hydroxymethylbilane

Hydroxymethylbilane (HMB), also known as preuroporphyrinogen, is a molecule involved in the metabolism of porphyrin. In the third step, it is generated by the enzyme porphobilinogen deaminase, and in the next step the enzyme uroporphyrinogen III synthase converts it into uroporphyrinogen III.

In general, defects of heme synthesis after formation of HMB lead to photosensitivity.

Category:Tetrapyrroles