Wiktionary
humulone
n. (context organic compound English) A bitter-tasting chemical compound found in the resin of mature hops (''Humulus lupulus'').
Wikipedia
Humulone
Humulone (α-lupulic acid), a vinylogous type of organic acid, is a bitter-tasting chemical compound found in the resin of mature hops ( Humulus lupulus). Humulone is a prevalent member of the class of compounds known as alpha acids, which collectively give hopped beer its characteristic bitter flavor.